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Unit outline_

NURS1005: Human Pathophysiology

Semester 2, 2026 [Normal day] - Camperdown/Darlington, Sydney

In this unit of study, students will explore the pathogenesis of human disease. Using a systems-based approach, the pathophysiology of common illnesses observed in the clinical setting will be examined. This will be studied in the context of the mechanisms that maintain homeostatic control of body processes. The topics of oxygenation, protection/immunity, metabolism, neuro-endocrine regulation, and elimination will be explored in the context of disease and disorders associated with these processes. This learning will extend students' understandings of complex physiological alterations and pathophysiology.

Unit details and rules

Academic unit Department of Medical Sciences
Credit points 6
Prerequisites
? 
NURS1001
Corequisites
? 
None
Prohibitions
? 
None
Assumed knowledge
? 

None

Available to study abroad and exchange students

No

Teaching staff

Coordinator Margot Day, margot.day@sydney.edu.au
The census date for this unit availability is 31 August 2026
Type Description Weight Due Length Use of AI
Written exam Assessment 3: Final examination
Short answer
40% Formal exam period 2 hours AI prohibited
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Early Feedback Task Assessment 1A: In class quiz
MCQ consisting of 10 questions in 12min in tutorials
5% Week 03
Due date: 21 Aug 2026 at 17:00
12 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Assessment 1B: In class quiz
Multiple choice quiz consisting of 10 questions in 12 min in practicals.
5% Week 04
Due date: 28 Aug 2026 at 17:00
12 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Assessment 1C: In class quiz
Multiple choice quiz consisting of 10 questions in 12 min in tutorials.
5% Week 05
Due date: 04 Sep 2026 at 17:00
12 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Assessment 1D: In class quiz
Multiple choice quiz consisting of 10 questions in 12 min in practicals.
5% Week 06
Due date: 11 Sep 2026 at 17:00
12 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Assessment 1E: In class quiz
Multiple choice quiz consisting of 10 questions in 12 min in tutorials.
5% Week 07
Due date: 18 Sep 2026 at 17:00
12 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
Case studies Assessment 2: Case study based assignment
Case study based assignment, individual work, based on content in weeks 1-6
30% Week 07
Due date: 20 Sep 2026 at 23:59
1500 words AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Assessment 1F: In class quiz
Multiple choice quiz consisting of 10 questions in 12 min in tutorials.
5% Week 08
Due date: 25 Sep 2026 at 17:00
12 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
early feedback task = early feedback task ?

Early feedback task

This unit includes an early feedback task, designed to give you feedback prior to the census date for this unit. Details are provided in the site and your result will be recorded in your Marks page. It is important that you actively engage with this task so that the University can support you to be successful in this unit.

Assessment summary

Formative Assessment:

  • Online modules: Students are required to complete the online modules throughout semester as per the kuracloud tutorial lessons.

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  • Assessment 1: Weekly quizzes:ÌýThese quizzes will test the key concepts taught each week and include the topics ofÌýdigestive physiology, metabolism and related alterations,Ìýrespiratory physiology and related alterations, and cardiovascular physiology and related alterations, immunity, infection and fever, CNS and PNS physiology and related alterations, and endocrine pysiology and related alterations. Quizzes run in weeks 3-8 inclusive during scheduled tutorial or practical time. The week 3Ìýquiz will be the #earlyfeedbacktask
  • Assessment 2: Case study based assignment: Students will be given one or more case studies,Ìýwhich they are expected to analyse, and answer a series of questions examining the alterations in physiology observed in the patient(s).Ìý This assessment will examine student’s pathophysiology knowledge and critical thinking skills.
  • Assessment 3: Examination: The examination will cover all aspects of the unit of study. The examination will assess the students’ understanding of alterations of physiological processes and pathophysiological phenomena in the health care setting.

Please note: Each student is required to submit all assessment items, and each submission needs to be of an assessable standard, in order to be eligible to pass this unit. Detailed information for each assessment can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Grade

Mark range

Description

High distinction

85 - 100

Awarded when you demonstrate the learning outcomes for the unit at an exceptional standard.

Distinction

75 - 84

Awarded when you demonstrate the learning outcomes for the unit at a very high standard

Credit

65 - 74

Awarded when you demonstrate the learning outcomes for the unit at a good standard

Pass

50 - 64

Awarded when you demonstrate the learning outcomes for the unit at an acceptable standard

Fail

0 - 49

When you don’t meet the learning outcomes of the unit to a satisfactory standard.

For more information see guide to grades.

Use of generative artificial intelligence (AI)

You can use generative AI tools for open assessments. Restrictions on AI use apply to secure, supervised assessments used to confirm if students have met specific learning outcomes.

Refer to the assessment table above to see if AI is allowed, for assessments in this unit and check Canvas for full instructions on assessment tasks and AI use.

If you use AI, you must always acknowledge it. Misusing AI may lead to a breach of theÌýAcademic Integrity Policy.

Visit theÌýCurrent Students websiteÌýfor more information on AI in assessments, includingÌýdetails on how to acknowledge its use.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

  • Deduction of 5% of the maximum mark for each calendar day after the due date.
  • After ten calendar days late, a mark of zero will be awarded.

This unit has an exception to the standard University policy or supplementary information has been provided by the unit coordinator. This information is displayed below:

Written work submitted electronically after 11.59 pm on the due date will be considered to have been submitted late. For every calendar day up to and including ten calendar days after the due date, a penalty of 5% of the maximum awardable marks will be applied to late work. The penalty will be calculated by first marking the work, and then subtracting 5% of the maximum awardable mark for each calendar day after the due date. For work submitted more than ten calendar days after the due date a mark of zero will be awarded. The marker may elect to, but is not required to, provide feedback on such work.

Academic integrity

The University expects students to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

Our websiteÌýprovides information on academic integrity and the resources available to all students. This includes advice on how to avoid common breaches of academic integrity. Ensure that you have completed theÌýAcademic Honesty Education Module (AHEM)Ìýwhich is mandatory for all commencing coursework students

Penalties for serious breaches can significantly impact your studies and your career after graduation. It is important that you speak with your unit coordinator if you need help with completing assessments.

Visit theÌýCurrent Students websiteÌýfor more information on AI in assessments, includingÌýdetails on how to acknowledge its use.

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through aÌýsimple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible forÌýspecial consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students,ÌýÌýincludes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

Support for students

The Support for Students PolicyÌýreflects the University’s commitment to supporting students in their academic journey and making the University safe for students. It is important that you read and understand this policy so that you are familiar with the range of support services available to you and understand how to engage with them.

The University uses email as its primary source of communication with students who need support under the Support for Students Policy. Make sure you check your University email regularly and respond to any communications received from the University.

Learning resources and detailed information about weekly assessment and learning activities can be accessed via Canvas. It is essential that you visit your unit of study Canvas site to ensure you are up to date with all of your tasks.

If you are having difficulties completing your studies, or are feeling unsure about your progress, we are here to help. You can access the support services offered by the University at any time:

Support and Services (including health and wellbeing services, financial support and learning support)
Course planning and administration
Meet with an Academic Adviser

WK Topic Learning activity Learning outcomes
Week 01 Metabolic reactions, biomolecules and energy production Lecture (1 hr) LO1 LO2
Digestive physiology Lecture (1 hr) LO1 LO2
Week 02 Alterations to digestive physiology Lecture (1 hr) LO2 LO3 LO4
Alterations to Digestion Tutorial (2 hr) LO1 LO2 LO3 LO4
Respiratory physiology Lecture (1 hr) LO1 LO2
Week 03 Alterations in ventilation and respiration Lecture (1 hr) LO2 LO3 LO4
Diseases of the respiratory system Practical (2 hr) LO1 LO2 LO3 LO4
Cardiovascular physiology Lecture (1 hr) LO1 LO2
Week 04 Alterations in cardiac contraction and conduction Lecture (1 hr) LO2 LO3 LO4
Cardiovascular disease Practical (2 hr) LO1 LO2 LO3 LO4
Neural physiology Lecture (1 hr) LO1 LO2
Week 05 Alterations to neural physiology Lecture (1 hr) LO2 LO3 LO4
Alterations in the central nervous system and peripheral nervous system Tutorial (2 hr) LO1 LO2 LO3 LO4
Blood physiology and blood dyscrasias Lecture (1 hr) LO1 LO2
Week 06 Non-specific and specific immunological responses, infection and fever Lecture (1 hr) LO2 LO3 LO4
Identifying immune cells by microscopy and immunohistology Practical (2 hr) LO1 LO2 LO3 LO4
Endocrine physiology Lecture (1 hr) LO1 LO2
Week 07 Alterations to endocrine physiology Lecture (1 hr) LO2 LO3 LO4
Endocrine disorders Tutorial (2 hr) LO1 LO2 LO3 LO4
Renal physiology and altered renal physiology Lecture (1 hr) LO1 LO2 LO3 LO4
Week 08 Alterations to fluid and electrolyte balance Lecture (1 hr) LO1 LO2 LO3 LO4
Renal disease Tutorial (2 hr) LO1 LO2 LO3 LO4

Attendance and class requirements

The Sydney Nursing School Attendance and Participation Provisions (2026) provide the framework for attendance and participation requirements across all coursework programs. Students are expected to familiarise themselves with these provisions, which outline their responsibilities for attending and participating in required learning activities, as well as the processes to follow if they are unable to attend.

View the SNS Attendance and Participation Provisions (2026):

Ìý

Attendance BN [AS]

  • Students are expected to attend, engage and participate in all scheduled classes and required learning activities. Students must notify the school if they are, or will be, unable to attend a required learning activity; and apply for special consideration or special arrangements; or have an academic plan with relevant adjustments, where appropriate. Students must apply for Special Consideration for absence from any scheduled required learning activity which includes an assessment.Ìý For additional information, please review the policy

Attendance and participation are monitored.

  • Students should attend and participate in all required learning activities in person, except for (a) pre-recorded lectures, which students may view in their own time; and (b) other sessions as specified by the unit coordinator. Students who fail to attend a required learning activity will be recorded as absent.
  • Students must attend/participate in any live/synchronousÌýlectures,Ìýand view any recorded lectures, specified as compulsory per unit of study.
  • Any anticipated absences or late arrivals should be clearly communicated to your unit of study coordinator as soon as possible. Your email should clearly state your name and the day and time you will be absent and should be emailed via your university email address; your unit of study coordinator will advise you accordingly.
  • ÌýStudents must attend/participate in minimumÌý90% of allÌýtutorial classesÌýscheduled per unit of study. At the discretion of the Unit of Study Coordinator, where relevant, an alternative (catch-up) learning activity may be approved and provided to students absent from tutorials due to unforeseen circumstances or with an approved planned absence. Any unexplained absences are a breach of professionalism, and a potential risk of not passing the unit of study. Not meeting attendance requirements could lead to an Absent Fail grade and referral to the School’s Student Professionalism Committee.

Ìý Ìý (i) maximum two tutorial absences permitted per unit of study where an approved alternative (catch-up) learning activity is completed.

Ìý Ìý (ii) where a student satisfactorily completes an approved alternative learning activity, this will be recorded.

  • Students must attend/participate inÌýall practical classesÌý(simulation labs and/or workshops) scheduled per unit of study.
  • At the discretion of the Unit of Study Coordinator, where relevant, an alternative (catch-up) learning activity may be approved and provided to students absent from practical classes due to unforeseen circumstances or with an approved planned absence: (i) maximum two practical class absences permitted per unit of study where an approved alternative (catch-up) learning activity is completed. (ii) where a student satisfactorily completes an approved alternative learning activity, this will be recorded.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

Craft, Gordon, Huether, McCance and Brashers.ÌýUnderstanding Pathophysiology: ANZ Edition (current ed.) Elsevier, Sydney (Electronic edition preferred)Ìý

Please note that more detail regarding weekly readings is available on the NURS1005 unit of study CANVAS site.

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

At the completion of this unit, you should be able to:

  • LO1. explain the normal physiology related to the specified organ systems studied and describe complex human physiology.
  • LO2. discuss homeostatic control and explain how compensatory mechanisms influence bodily functions during health and illness.
  • LO3. describe the pathogenesis of the common diseases/disorders of each organ system studied.
  • LO4. identify the changes in pathophysiology associated with common illness and disease and correlate these with the resulting signs, symptoms observed.

Graduate qualities

The graduate qualities are the qualities and skills that all ±¬ÁÏÍõ graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1 Depth of disciplinary expertise

Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.

GQ2 Critical thinking and problem solving

Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.

GQ3 Oral and written communication

Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.

GQ4 Information and digital literacy

Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.

GQ5 Inventiveness

Generating novel ideas and solutions.

GQ6 Cultural competence

Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.

GQ7 Interdisciplinary effectiveness

Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.

GQ8 Integrated professional, ethical, and personal identity

An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.

GQ9 Influence

Engaging others in a process, idea or vision.

Outcome map

Learning outcomes Graduate qualities
GQ1 GQ2 GQ3 GQ4 GQ5 GQ6 GQ7 GQ8 GQ9

Alignment with Competency standards

Outcomes Competency standards
LO1
Registered Nurses Standards for Practice - NMBA
1. Standard 1: Thinks critically and analyses nursing practice
3.7. Identifies and promotes the integral role of nursing practice and the profession in influencing better health outcomes for people
6. Standard 6: Provides safe, appropriate and responsive quality nursing practice
6.1. Provides comprehensive safe, quality practice to achieve agreed goals and outcomes that are responsive to the nursing needs of people
LO2
Registered Nurses Standards for Practice - NMBA
1. Standard 1: Thinks critically and analyses nursing practice
3.7. Identifies and promotes the integral role of nursing practice and the profession in influencing better health outcomes for people
5. Standard 5: Develops a plan for nursing practice
6. Standard 6: Provides safe, appropriate and responsive quality nursing practice
6.1. Provides comprehensive safe, quality practice to achieve agreed goals and outcomes that are responsive to the nursing needs of people
6.5. Practises in accordance with relevant nursing and health guidelines, standards, regulations and legislation
7. Standard 7: Evaluates outcomes to inform nursing practice
LO3
Registered Nurses Standards for Practice - NMBA
1. Standard 1: Thinks critically and analyses nursing practice
3.7. Identifies and promotes the integral role of nursing practice and the profession in influencing better health outcomes for people
6. Standard 6: Provides safe, appropriate and responsive quality nursing practice
6.1. Provides comprehensive safe, quality practice to achieve agreed goals and outcomes that are responsive to the nursing needs of people
6.3. Appropriately delegates aspects of practice to enrolled nurses and others, according to enrolled nurse’s scope of practice or others’ clinical or nonclinical roles
6.5. Practises in accordance with relevant nursing and health guidelines, standards, regulations and legislation
7. Standard 7: Evaluates outcomes to inform nursing practice
LO4
Registered Nurses Standards for Practice - NMBA
1. Standard 1: Thinks critically and analyses nursing practice
3.7. Identifies and promotes the integral role of nursing practice and the profession in influencing better health outcomes for people
5. Standard 5: Develops a plan for nursing practice
5.2. Collaboratively constructs nursing practice plans until contingencies, options priorities, goals, actions, outcomes and timeframes are agreed with the relevant persons
6. Standard 6: Provides safe, appropriate and responsive quality nursing practice
6.1. Provides comprehensive safe, quality practice to achieve agreed goals and outcomes that are responsive to the nursing needs of people
6.3. Appropriately delegates aspects of practice to enrolled nurses and others, according to enrolled nurse’s scope of practice or others’ clinical or nonclinical roles
6.5. Practises in accordance with relevant nursing and health guidelines, standards, regulations and legislation
7. Standard 7: Evaluates outcomes to inform nursing practice
Registered Nurses Standards for Practice -
Competency code Taught, Practiced or Assessed Competency standard
1.1 A Accesses, analyses, and uses the best available evidence, that includes research findings for safe quality practice
2.4 A Provides support and directs people to resources to optimise health related decisions
3.2 A Provides the information and education required to enhance people’s control over health
3.3 A Uses a lifelong learning approach for continuing professional development of self and others
6.1 A Provides comprehensive safe, quality practice to achieve agreed goals and outcomes that are responsive to the nursing needs of people

This section outlines changes made to this unit following staff and student reviews.

Practicals have been incorporated to include an active learning component, in which the students make physiological measurements in class on themselves and their peers. Data from these measurements is then related to real patient data and case studies. This will help students to analyse and interpret patient data and relate it to alterations that can occur to normal human physiology. Number of students in tutorials has been reduced to enable access to the Pathology museum and to facilitate in-class discussion with the tutors.

Sensitive materials in teaching:ÌýPlease note that in this Unit of Study sensitive and potentially distressing or disturbing content might be presented and/or discussed from time to time. This may include reference to for example, discrimination, assault, suicide, illness, death and dying or culturally sensitive issues. These topics are relevant to your learning and your knowledge and skill development for nursing practice.

You will be advised before the information/topic is presented. If you are participating in the teaching session/activity online, you are advised to use headphones and ensure that anyone not participating in the session cannot see images that you may be watching on your device. If the nature of the content makes you feel uncomfortable or distressed, it is important that you contact the unit coordinator or another member of the academic team to discuss this with them. Ìý

Disclaimer

Important: the ±¬ÁÏÍõ regularly reviews units of study and reserves the right to change the units of study available annually. To stay up to date on available study options, including unit of study details and availability, refer to the relevant handbook.

To help you understand common terms that we use at the University, we offer an .