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Drug-resistant XDR typhoid on our doorstep

18 September 2019
Improvements needed in travel health planning
MBI researchers report Australia's first case of extensively drug-resistant (XDR) typhoid

聽the聽first case of XDR typhoid identified in Australia. A 20鈥恗onth鈥恛ld Australian鈥恇orn girl presented to the Children's Hospital at Westmead with features of enteric fever 14 days after her return from a 3鈥恗onth trip to Karachi. Diarrhoea began in Pakistan 6 weeks before her return, and continued despite the use of oral antibiotics prescribed locally in Pakistan. Ten days of high fevers, irritability, vomiting and reduced oral intake prompted admission to our hospital. She was a previously well child and had received routine vaccines. No additional pre鈥恡ravel vaccinations had been recommended.聽The child responded to intravenous meropenem and oral azithromycin and was discharged a week after admission.

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