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• Professor Adron Harris leads of large research group at the Waggoner Center for Alcohol & Addiction Research at The University of Texas at Austin. They are investigating the molecular actions of drugs of abuse on brain signaling systems and the genetics of alcohol susceptibility. Along with his associates Dayne Mayfield and Igor Ponomarev are applying new genomic tools for profiling alcohol use disorders.
  
• Professor Fulton Crews, the director of the UNC Bowles Center for Alcohol Studies heads a dynamic group investigating how the impact of chronic drinking induces structural and functional changes associated with binge drinking. Recent studies have suggested that neuroinflammation may contribute to degeneration and loss of neurogenesis during binge drinking. They have also found that heavy alcohol use damages cortical brain regions associated with impulse control and planning capabilities.
• Professor Georgy Bakalkin’s group at the Department of Pharmaceutical Biosciences, Uppsala University are researching the endogenous opioid system (EOS) that has been strongly implicated in the positive and negative reinforcing effects of alcohol.
  
• Dr Greg Sutherland from The ±¬ÁÏÍõ, in collaboration with Professor Jillian Kril, is investigating neurogenesis in the alcoholic brain. Evidence from rodents suggests that chronic alcohol consumption impairs brain neurogenesis, but it is unclear whether this is the case in humans, or indeed whether significant neurogenesis occurs in older adult brains.

Dr Kelly Newell is based at The University of Wollongong. Her research focuses on the molecular mechanisms underlying psychiatric disorders including schizophrenia and depression as well as identify and investigate the potential of novel therapeutic targets for the treatment of psychiatric disorders. Dr Newell's research aims to understand Dr Newell has a strong interest in the glutamatergic system and its relevance to psychiatric illness and the implication of the metabotropic glutamate system in particular, in both the pathology and treatment of psychiatric illness.

Professor Kril is a chief investigator in a program of research led by Professor Glenda Halliday on the pathogenesis of frontotemporal dementia (FTD) and motor neurodegenerative syndromes, investigating the associated proteinopathies and clinicopathological correlations. The ultimate goal of this research program is to develop a platform for therapeutic intervention with disease-modifying therapies. This requires an understanding of the pathogenesis of the protein abnormalities to be treated, as well as the ability to clinically identify the patients with the various proteinopathies.

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