爆料王

鈥淭here was agreement across prescriber groups that joint action on antimicrobial resistance is needed but they tend to see the role of others as having a greater responsibility,鈥� says of the 爆料王, who led the research published in today's

鈥淥n the plus side, prescribers are quite knowledgeable about antimicrobial resistance and are aware of its connections between human, animal and environmental ecosystems.鈥�

Antimicrobial resistance (AMR) has developed through the overuse and misuse of antibiotics so that bacterial infections that were once easily cured with antibiotics are becoming harder to treat.

It threatens the effective prevention and treatment of an increasing range of infections caused by bacteria, parasites, viruses and fungi.

This matters because AMR is a significant challenge for the delivery of safe, high-quality healthcare, and has a direct impact on patient care and health outcomes.

In 2014, and the threat of antimicrobial resistance has the potential to affect every individual.

The survey of 1330 doctors, dentists and veterinarians was broadly representative of each national workforce and identified many common and context-specific barriers to better prescribing practices by clinicians.

For example, factors rated as 鈥渟omewhat鈥� of a barrier that were common across professions included:

• lack of patient understanding about antibiotics
• fear of blame for failure to prescribe if antibiotics were later proven to be necessary
• difficulty of making an accurate diagnosis
• lack of clear guidelines for some conditions
• and fear of missing an infection.

鈥淭hese common barriers indicate broader challenges across professions and settings,鈥� says co-author, of the University of Technology, Sydney.

鈥淭hese highlight the need for greater public awareness of antimicrobial resistance and a need to reduce diagnostic uncertainty by developing faster and more accessible diagnostic tests to limit the need for risk averse strategies such as prescribing unnecessarily, or 鈥榡ust in case鈥欌��.

Key findings

• All prescriber groups rated AMR as a 鈥渟ignificant鈥� problem to the health of patients in human hospitals and residents in nursing homes and aged care facilities
• All groups reported that patients鈥� clinical signs and symptoms strongly influenced their prescribing decisions. For example, patients described as critically ill or immunocompromised were rated as a 鈥渟trong influence鈥� among all groups, especially doctors
• Bacterial culture and susceptibility test results were rated as a 鈥渟trong influence鈥� on doctors鈥� and veterinarians鈥� decisions to prescribe antibiotics or not, and as exerting 鈥渘o influence鈥� or being 鈥渘ot applicable鈥� among dentists
• Doctors were generally more aware, than dentists or veterinarians, that a single course of antibiotics could lead to resistance and that resistant bacteria may persist for up to year in a patient after a single use of antibiotics
• Contrary to existing research findings and despite respondents perceiving public education as a 鈥渧ery helpful鈥� measure in supporting appropriate prescribing, respondents did not consider commonly reported barriers such as patient/client pressure and expectations as having a 鈥渟ignificant鈥� influence on their prescribing behaviours.